Herbal drugs and phytopharmaceuticals. Avoid use. Contact your doctor or pharmacist if you have any questions before use. The leaves and stems of comfrey contain pyrrolizidine alkaloids that can cause toxic damage if ingested in excess (Ulbricht, 2010). Symphyti) in the treatment of ankle distorsions: results of a multicenter, randomized, placebo-controlled, double-blind study. (2013). It has bell-shaped red-violet or yellowish flowers. Palestrica of the Third Millennium Civilization & Sport. Comfrey Uses, Benefits & Side Effects - Drugs.com Herbal Database Store comfrey cream according to package instructions, typically at room temperature and out of reach of children and pets. Some of these components are thought to speed up wound healing by stimulating new cell growth. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Browse our Sports Hub, Get 20% student discount with Student Beans, Discover the latest natural beauty products. Comfrey. The ointment has a very mild herbal fragrance and is soothing on application. The following applications have been used in research: Using large amounts of comfrey cream or using it for extended periods of time increases the risk of side effects like liver toxicity. Browse our Sports Hub, Get 20% student discount with Student Beans, Discover the latest natural beauty products, Buy 1 get 1 Half Price on Vitamins & Supplements, Popular Vitamins & Supplements Subscriptions, Buy 1 get 1 Half Price gut health supplements, Guide to sleeping better natural sleeping remedies, Living in the now, gut health & mental wellbeing, The thing that makes you different makes you special, For the symptomatic relief of minor sprains and bruises, Contains Comfrey which is known for its healing properties. After the consistency begins to thicken, turn the mixer up a little bit. comfrey cream holland and barrett - daxasys.com doi:10.1002/14651858.CD010538, Smith DB, Jacobson BH. Topical preparations of comfrey are generally safe provided they are not applied excessively or to an open wound. comfrey: [noun] any of a genus (Symphytum) of perennial herbs of the borage family with coarse hairy entire leaves and flowers in one-sided racemes. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. WMW Wiener Medizinische Wochenschrift, 154(21), 498-507. https://link.springer.com/article/10.1007/s10354-004-0114-8, Natural Medicines (2020). The cream was applied to the local lumbar area 4x during the day of the exercise, with the first application being pre-exercise (Jurcau & Jurcau, 2013). My family has used comfy for ingrown toenails. J Pharmacopuncture 2021;24(4):196-205. With extract of Comfrey. Giannetti, B. M., Staiger, C., Bulitta, M., & Predel, H. G. (2010). View abstract. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements. hollandandbarrett.ie is a trading name of Holland & Barrett Retail Limited. Heard about essential oils but not quite sure about what they can do for you? 2012;101(4):211-216. View abstract. (2013). 2010;44(9):637-41. doi:10.1136/bjsm.2009.058677, Cameron M, Chrubasik S. Topical herbal therapies for treating osteoarthritis. Readers must do their own research concerning the safety and usage of any herbs or supplements. 2013;21(6):724-745. doi:10.1016/j.ctim.2013.09.009. A handbook for practice on a scientific basis. Cochrane Database Syst Rev. It can grow up to 5 feet tall. Phytother Res. Comfrey: Uses, Risks, and Takeaways - Healthline As a Licensed Massage Therapist for fifteen years, I have noticed that back pain can be caused by a variety of reasons and can be very debilitating. 2012;20(11):1209-1216. Topical preparations of comfrey are generally safe provided they are not applied excessively or to an open wound. Since these toxic substances can be absorbed through the skin, there's concern about the safety of comfrey cream applied topically. 2007;14(1):2-10. Wien Med Wochenschr. It's typically only used in small amounts for a very short period. They help us to understand how people use the website and give us the ability to provide targeted marketing to you. Poisons Legislation Circular 3-22-1993;60. comfrey cream holland and barrett. Koll, R., Buhr, M., Dieter, R., Pabst, H., Predel, H. G., Petrowicz, O., Giannetti, B., Klingenburg, S., and Staiger, C. Efficacy and tolerance of a comfrey root extract (Extr. What alternatives to comfrey cream are there for back pain? It contains chemicals that are poisonous. Comfrey cream, an topical herbal product, is thought to reduce inflammation and pain when applied to the skin. This is not a complete list of side effects and others may occur. Learn more in The Comfrey Controversy: Can and Should One Use Comfrey Internally? Other uses not proven with research have included skin wounds, skin ulcers, cough, sore throat, gum disease, joint pain, diarrhea, and other conditions. Nyman) in children: A randomized double-blind study. Stewart MJ, Steenkamp V. Pyrrolizidine poisoning: a neglected area in human toxicology. Affiliate links are shared throughout the website and the Herbal Academy may receive compensation if you make a purchase with these links. Complement Ther Clin Pract. Potters Comfrey Oil | Holland & Barrett Available for Android and iOS devices. Comfrey is a fast-growing plant whose leaves and roots have been used historically for wound healing and other conditions. Additionally, because its alkaloids are absorbed through the skin, use of comfrey as a poultice should not exceed an exposure of 100 mcg/day of the alkaloids. Megan Nunn, PharmD, is a community pharmacist in Tennessee with twelve years of experience in medication counseling and immunization. Mazzocchi, A. and Montanaro, F. Observational study of the use of Symphytum 5CH in the management of pain and swelling after dental implant surgery. Comfrey Uses, Side Effects & Warnings - Drugs.com Be sure to use comfrey root from a reputable source that has properly identified the species. Commercial comfrey sale and distribution is restricted in Germany and Canada because of its substantial toxicity. As we are constantly reviewing and developing our products to meet our consumer needs, consumers, particularly those that suffer from allergies and intolerances, should always check product labelling, warnings, and directions provided with the product that is delivered, prior to use or consumption. Tanret, I. and Duh, D. [Pharmaceutical sheet. International Journal of Pediatrics and Adolescent Medicine, 5(4), 135-141. https://doi.org/10.1016/j.ijpam.2018.11.002, Kuera, M., Barna, M., Horek, O., Kovrikov, J., & Kuera, A. Comfrey is traditionally used for the symptomatic treatment of minor sprains and bruises and is also known for its healing properties Customer Reviews Ingredients Full ingredients Brassica Campest is Seed Oil (Rapeseed Oil), Symphytum Officinale Herb (Comfrey Herb), BHA, Eucalyptus Globulus Leaf Oil (Eucalyptus Oil). Kuera, M., Barna, M., Horek, O., Kovrikov, J., & Kuera, A. The most common over-the-counter medication that can be toxic to the liver is acetaminophen (Tylenol). If you're considering using the cream, consult your healthcare provider first. You may report side effects to FDA at 1-800-FDA-1088. Symphytum officinale L., dermal use (Flexagile cream)]. Mosby Elsevier. Consult your healthcare provider before using. Comfrey cream combines ingredients like oils or water and glyceryl stearate with Symphytum officinale (comfrey) extracts. Buy 1 get 1 Half Price | Plus an extra 20% off 30, Shop buy 1 get 1 half price on all gut health products, Looking for fitness advice & inspiration this New Year? Phytomedicine, 14(1), 2-10. https://doi.org/10.1016/j.phymed.2006.11.006, Jedlinszki, N., Balzs, B., Csnyi, E., & Csupor, D. (2017). Inhibition of prostaglandin biosynthesis and PAF-induced exocytosis. Stop using comfrey and call your healthcare provider at once if you have: liver problems-- nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). 2013;21(6):724-45. Symphyti) in the treatment of ankle distorsions: Results of a multicenter, randomized, placebo-controlled, double-blind study. Anotherstudy found that comfrey ointment was superior to placebo in relieving pain and stiffness in osteoarthritis. Modern science suggests that the ancients were correct in believing comfrey helps to heal woundsand relieve pain.3,4 In this article, well explain where comfrey comes from, comfrey oils remarkable health benefits and how to use it at home. Taking comfrey along with a medication that can harm the liver might increase the risk of liver damage. Comfrey contains toxic substances that cause liver damage, cancer, and death. Vithayathil MK, Edwards M. Comfrey herbal remedy causing second-degree heart block: do not be outfoxed by digitalis. Be sure to choose organic carrier oils and essential oils when possible. Comfrey contains chemicals called. Influence of moderate physical exertion on subacute low back pain, after Symphytum officinale ointment treatment. Comfrey is a plant also known as Ass Ear, Black Root, Blackwort, Bruisewort, Consolidae Radix, Consound, Consoude, Consuelda, Gum Plant, Healing Herb, Herbe aux Charpentiers, Herbe la Coupure, Knitback, Knitbone, Langue-de-Vache, Oreille d'ne, Salsify, Slippery Root, Symphytum officinale, or Wallwort. Herbal medicine for low back pain: A Cochrane review, Dietary Supplements: What You Need to Know, Sinusoidal obstruction syndrome (blockage of veins in the liver). Preclinical studies suggest that oral comfrey has antiproliferative effects , and a topical formulation showed wound healing properties . Beth Thomas, PharmD, is a clinical pharmacist and founder of BMT Consulting Services, LLC. This is memorable if you have worked with it, and some use this quality to remember comfreys centuries-long useapplying comfrey over bones, bruises, sprains, and minor wounds with the intention to support mending! Phytomedicine 2005;12(10):707-714. View abstract. This could change the effects and side effects of comfrey. Consult your healthcare provider before using comfrey cream. Food and Drug Administration. Many of those following the folk use of comfrey up to present-day think so. Comfrey cream contains several active components (substances). 2018;19(5):455-474. doi:10.1016/j.jpain.2017.11.005, Gagnier JJ, Oltean H, van Tulder MW, Berman BM, Bombardier C, Robbins CB. Thus, it is not advised to ingest herbal preparations of comfrey unless guided by an expert pharmacologist and physician. Herb & Supplement Guide. An Evidence-Based Reference. Comfreycontains PAs, substances that can cause significant damage, including: Therefore, it should never be taken by mouth. randomized double-blind study of 278 patients with fresh abrasions, a. topical preparation containing a 10% comfrey leaf extraction applied for 2-3 days reduced wound healing time of adults and children without side effects (Barna et al., 2012). reduce lower back pain (Stam et al., 2001). Comfrey oil is made by infusing the leaves and roots of a comfrey plant with a neutral oil. Heat oil in double boiler gently then add beeswax until it melts. Its long, lance-shaped leaves can be up to 1 foot in length closer to the bottom of the stem and are shorter higher up the stem. View abstract. randomized, placebo-controlled, double-blind, multi-clinical trial. Phytomedicine. Comfrey flowers are bell-shaped and purple, pink, or pale yellow in color, and it has a dark taproot. Z Phytotherapie 2000;21:127-134. Dietary supplements are not regulated like drugs in the United States, meaning the Food and Drug Administration (FDA) does not approve them for safety and effectiveness before products are marketed. One study in 120 patients with acute upper or lower back pain used either four grams (g) of comfrey root ointment or a placebo (sham treatment) three times daily for five days. This comfrey cream recipe works great for local areas that have mild bruising or soft tissue pain. Complement Ther Med. Huxtable RJ, Awang DV. It contains chemicals that are poisonous. Please review this supplement label with your healthcare provider to discuss potential interactions with foods, other supplements, and medications. Comfrey - The Lost Herbs Medicine makers would bind comfrey leaves and roots in poultices, then apply those poultices to the skin to treat injuries. This is the tincture. Its long, lance-shaped leaves can be up to 1 foot in length closer to the bottom of the stem and are shorter higher up the stem. Oral use of comfrey is not recommended because of potential liver damage. View abstract. Phytother Res. radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee: Results of a double-blind, randomised, bicenter, placebo-controlled trial. Squish and squeeze as many leaves into as you can into the container. After the tincture is made, then you can whip up the fabulous joint and muscle cream! Recent studies have suggested topical benefits, but more research is needed. It is called knitbone or boneset, referring to the bone-like growth of its roots. Check regularly, but it should take about six weeks for all the leaves to break down into a thick, black liquid. Mei N, Guo L, Fu PP, Fuscoe JC, Luan Y, Chen T. Metabolism, genotoxicity, and carcinogenicity of comfrey. Influence of moderate physical exertion on subacute low back pain, after Symphytum officinale ointment treatment. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Do not use this product without medical advice if you are pregnant. Drug class: Herbal products. View abstract. Barna, M., Kucera, A., Hladikova, M., & Kucera, M. (2012). The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Rad. MedlinePlus Medical Encyclopedia. Mix for about 10 minutes, until nice and whipped. View abstract. Staiger, C. Comfrey: a clinical overview. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Efficacy and safety of topically applied Symphytum herb extract cream in the treatment of ankle distortion: Results of a randomized controlled clinical double-blind study. Comfrey [Online article]. Version: 5.01. If your healthcare provider recommends it, make sure to use it on intact skin for a small amount of time, and be careful that infants do not ingest it. After eight days, the group that used the cream had significantly less pain than those who had the placebo. Comfrey - please don't use it - The Herbal Horse and Pet Pyrrolizidine alkaloids are very toxic to the liver and are also carcinogenic (cause cancer). It may contain small amounts of toxic pyrrolizidine alkaloids. DOI:10.1211/PJ.2021.1.69803. Barna, M., Kucera, A., Hladikova, M., and Kucera, M. Randomized double-blind study: wound-healing effects of a Symphytum herb extract cream (Symphytumxuplandicum Nyman) in children. Links to external sites are for informational purposes only. Comfrey Cream: Uses, Benefits, Side Effects, Dosage - Verywell Health Barthomeuf, C. M., Debiton, E., Barbakadze, V. V., and Kemertelidze, E. P. Evaluation of the dietetic and therapeutic potential of a high molecular weight hydroxycinnamate-derived polymer from Symphytum asperum Lepech. After testing their 1000mg CBD oil drops for over a month, we now have little question this is the best CBD oil within the UK as of 2019. Dietary Supplements: What You Need to Know. Comfrey - Memorial Sloan Kettering Cancer Center These third-party organizations test products to ensure they were manufactured safely and contain the ingredients indicated on the labeling without contaminants. Comfrey might harm the liver. Ingesting cooking oil has been banned by the European Union, due to a high risk of liver toxicity.9, Adults with liver disease, cancer, or a history of alcoholism are also advised to avoid comfrey because the skin can also absorb the liver-damaging compounds. Penetration of lycopsamine from a comfrey ointment through human epidermis. Additionally, there is scientific research demonstrating comfreys effectiveness at soothing muscle and joint pain, some of which are highlighted in this post. Finally, well warn of any side effects associated with comfrey oil. Copyright 1996-2023 Cerner Multum, Inc. Glass bowl with a lid The efficacy and safety of a homeopathic gel in the treatment of acute low back pain: a multi-centre, randomised, double-blind comparative clinical trial. Although topical comfrey has been used for this indication, there's little evidence that it helps and can pose a big risk for nursing babies. Smith, D. B., & Jacobson, B. H. (2011). Lewis, C. J. FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. 2014;20(4):347-55. Cover, but leave a small air opening. British Homeopathic Journal, 90(01), 21-28. https://doi.org/10.1054/homp.1999.0460. A systematic review and quality assessment of case reports of adverse events for borage (Borago officinalis), coltsfoot (Tussilago farfara) and comfrey (Symphytum officinale). For External Use only Do not use if you are sensitive to any of the ingredients. Do not use comfrey with very young children or during pregnancy or lactation. Wound-healing effects of a symphytum herb extract cream (Symphytum uplandicum Nyman) in children: A randomized double-blind study. 2016 Jan;41(2):116-33. doi:10.1097/01.brs.0000249525.70011.fe. Koll R, Klingenburg S. [Therapeutic characteristance and tolerance of topical comfrey preparations. Its ready when the mixture has solidified somewhat and has a cloudy, creamy, and slightly runny consistency. Nat Prod Res 2018;32(5):605-9. doi: 10.1080/14786419.2017.1326492. Some people ingest comfrey roots or leaves or use them in teas. 2008;54(1):7-20. Company number 02758955 Registered VAT number 211727395. View abstract. hollandandbarrett.com is a trading name of Holland & Barrett Retail Limited,. Toe was infected and painful. This is done by soaking the root in at least 50% alcohol for a minimum of two weeks. The chemicals contained in comfrey may cause birth defects. Grube, B., Grnwald, J., Krug, L., & Staiger, C. (2007). Skip the missed dose if it is almost time for your next scheduled dose. This is because only a small amount of the pyrrolizidine alkaloids are absorbed through the skin (. Symphyti) in the treatment of ankle distorsions: Results of a multicenter, randomized, placebo-controlled, double-blind study. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. cup organic safflower oil This is because only a small amount of the pyrrolizidine alkaloids are absorbed through the skin (Jedlinszki et al., 2017). Comfrey has been claimed to heal gastric ulcers and hemorrhoids, and to suppress bronchial congestion and inflammation. The herbal topical cream was prepared at two different strengths, as an additional measure of efficacy. All rights reserved. To make this recipe, first, you must prepare the comfrey root tincture. Shop buy 1 get 1 half price on all gut health products, Buy 1 get 1 Half Price | Plus an extra 20% off 25, App Exclusive | Get an extra 22% off 25 when you spend on the H&B App, Royal Mail strikes may cause a delay to our click and collect service, Looking for fitness advice & inspiration this New Year? Retrieved from, https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=295. Additionally, use on a deep cut may encourage healing of the outer skin the preparation comes in direct contact with faster than the deeper tissue, leading to abscess. Of course, more research is needed to validate efficacy and safety. View abstract. about an hour two nites. Understand comfreys contraindications before using it. 211727395. Koll, R., Buhr, M., Dieter, R., Petrowicz, O., Gianetti, B., and Wagener, S. Wirksamkeit und Vertraglichkeit von Beinwellextrakt (Extr. Make sure to always buy comfrey (Symphytum officianale) root and leaf from a trusted source. Frost R, O'meara S, Macpherson H. The external use of comfrey: a practitioner survey. Bleakley, C. M., McDonough, S. M., and MacAuley, D. C. Some conservative strategies are effective when added to controlled mobilisation with external support after acute ankle sprain: a systematic review. Comfrey has been used in alternative medicine as a possibly effective aid in treating back pain, osteoarthritis, or tenderness and swelling caused by a sprain injury. ). Apply a small amount (not to exceed a teaspoon) topically 2-3x/day for up to 2 weeks. 2012;62(6):285-289. radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee: results of a double-blind, randomised, bicenter, placebo-controlled trial. This recipe is contraindicated for small children and those with certain medical conditions. View abstract. Other herbal supplements that may have benefits for back pain include: Some other supplements that may be useful for osteoarthritis are: Back pain is often treated with medication such as over-the-counter pain relievers. Sowa I, Paduch R, Strzemski M, et al. One study followed 142 patients with ankle sprains. 2012;(1):41-42. Follow all directions on the product label and package. Kucera, M., Kalal, J., and Polesna, Z. Tunon, H., Olavsdotter, C., and Bohlin, L. Evaluation of anti-inflammatory activity of some Swedish medicinal plants. Transfer the cooled oil and butter mixture to a standing electric mixer or blender. In 2001, the Food and Drug Administration (FDA) banned oral comfrey products. View abstract. Complementary Health Approaches for Chronic Pain: What the Science Says. In some cases, ointments with comfrey have caused redness, itching, and a rash (Smith, 2011). Thus, it is not advised to ingest herbal preparations of comfrey unless guided by an expert pharmacologist and physician. The first European settlers of America considered comfrey so indispensable, they carried it on their journey across the Atlantic in the 1600s.2. Click to share on Facebook (Opens in new window), Click to share on Pinterest (Opens in new window), Click to share on Twitter (Opens in new window), Click to share on LinkedIn (Opens in new window), Click to share on Tumblr (Opens in new window), Click to share on Reddit (Opens in new window), Click to email a link to a friend (Opens in new window), Try A Cooling Herbal Compress for Hot Summer Days, Handmade Floral Paper: A Family-Friendly Project, Making Herbal Preparations 101 Mini Course, Emulsifiers and Preservatives in Botanical Skin Care Products. New South Wales Health, Australia. Hepatology. Although not examined in clinical trials, comfrey may possess antifungal and anticancer activity. Discard after a year or according to labeling. Mackinnon, M. In general practice, 'always expect the unexpected'. (2004). Not all possible interactions are listed in this product guide. J Agric.Food Chem 2001;49(8):3942-3946. We comply with the HONcode standard for trustworthy health information. Please read the Topical Use Safety section of this article (above) before using. We cover all you need to know in this article. (Grube et al., 2007). Double boiler Comfrey (Symphytum officinale) is a plant with yellow or purple flowers found in Europe, Asia, and North America. Some drugs increase how quickly the liver changes and breaks down comfrey. More research is needed. Further study is needed to confirm these results. To make this recipe, first, you must prepare the comfrey root tincture. At least three human studies found that the topical use of a cream containing comfrey root extract may safely help with pain, swelling, and mobility symptoms associated with an ankle sprain. A multi-center, randomized, double-blind, controlled clinical trial was conducted with 161 patients having acute lower back pain. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments. Fitoterapia. Terry Naturally Traumaplant Comfrey Cream - amazon.com 2012;20(11):1209-16. doi:10.1016/j.joca.2012.07.019, Zago LR, Prado K, Benedito VL, Pereira MM. The FDA has recommended that all comfrey products that are taken by mouth be removed from the market. 4.3 4.3 out of 5 stars (225) $19.95 $ 19. And topical capsaicin cream may help to relieve pain temporarily. Phytomedicine, 11(6), 470-477. https://doi.org/10.1016/j.phymed.2004.02.001, Kucera, A., Barna, M., Holcova, S., Horacek, O., Hladikov, M., & Ottillinger, B. These side effects may be common or severe. Copyright Holland & Barrett Retail Limited, 2022. Cbd Oil In Holland And Barrett. The Food and Drug Administration (FDA) released an advisory in July 2001 recommending that comfrey products be removed from the market because of cases of hepatic veno-occlusive disease. Generic name: comfrey [COM-free] J Pharm.Belg. COMFREY: Overview, Uses, Side Effects, Precautions - WebMD Potter's Herbals Comfrey Ointment for Minor Sprains and Bruises The groups using the herbal preparations reported a significantly greater reduction in pain and stiffness associated with osteoarthritis of the knee without serious adverse reactions (Smith & Jacobson, 2011). This includes androstenedione, bishop's weed, borage, chaparral, comfrey, DHEA, echinacea, garlic, germander, golden ragwort, hound's tongue, kava, licorice, niacin (vitamin B3), pennyroyal oil, red yeast, St. John's wort, and others. Experts suggest not using comfrey cream for longer than ten days in a row. This was compared to 37.8% in the placebo group. Latest: Senior Software Engineer - Front End Senior Software Engineer Senior Product Manager - Basket, Checkout and Payments UX Designer - Instore Tech. How to Make and Use Comfrey Fertilizer - The Spruce NIH Office of Dietary Supplements. It is not certain whether comfrey is effective in treating any medical condition. 2010;13(7-8):509-526. doi:10.1080/10937404.2010.509013, Staiger C. Comfrey: A clinical overview. Topically applied comfrey oil is associated with a wide range of health benefits and can help with certainissues including: Comfrey oil is good at helping with superficial cuts, scratches, and scrapes. 2020;142:104519. Healthy adults: massage about 1 teaspoon of cream into a local area up to 4x/day for up to 2 weeks. Wien Med Wochenschr. Tolerability and effectiveness of an antitrauma cream with comfrey herb extract in pediatric use with application on intact and on broken skin. To Use. Comfrey is generally considered unsafe, with numerous toxicological effects in animals and humans.
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