You should not be treated with this medicine if you have ever had an allergic reaction to an iron injection. For example, if someone takes 100 mg of a drug, only half of it will be in the bloodstream in a couple ofhours. Details. Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Venofer only for the indication prescribed. This medication passes into breast milk. If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. The use of Injectafer and Feraheme in treating IDA in these adults has been directly compared in a clinical study. Injectafer helps to treat IDA by providing an iron infusion directly into your body. These symptoms can include: While youre taking Injectafer, your doctor will monitor your phosphorus levels if youre at risk for hypophosphatemia. Injectafer is a brand-name prescription drug. 12 Medicines That Could Help, List Venofer Vial side effects by likelihood and severity. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. Medically reviewed by Sanjai Sinha, MD. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. Injectafer is approved to treat iron deficiency anemia (IDA). They have been a god send. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Venofer. Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. But they wont receive a total cumulative dose of more than 1,500 mg of Injectafer. Tell your caregivers right away if you have: problems with your dialysis vein access point; high blood pressure - severe headache, blurred vision, pounding in your neck or ears; low blood pressure - a light-headed feeling, like you might pass out; or. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Tell all of your health care providers that you take Venofer. However, since peoples bodies react so differently to drugs, they often have to change their stance on certaindrugs. Sharing this information can help you avoid potential interactions. But the length of time that this may take varies from person to person. Always review your medical history with the treatingphysician. What are the possible side effects of Venofer? | Nutritive Agent And the drug has also been studied in children with IDA who have inflammatory bowel disease (IBD). These nutrients include iron, vitamin B12, and folate. 2022 American Regent, Inc.PP-VE-US-0016 (v6.0)1/2022, Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your organs and tissues through hemoglobin, If you or your child has been prescribed Venofer, its based on your blood work, which shows how many red blood cells you have and whether you have enough iron in your blood cells, If you are iron deficient, raising your iron levels can help increase your hemoglobin levels, Treating your anemia may help prevent future health problems, Over time, untreated IDA can cause heart problems; if you already have heart problems, it can make those problems worse, Venofer is given intravenously (through an IV) and With a delayed reaction, your body reacts to a drug that youve been exposed to in the past without having a reaction. Venofer (Iron Sucrose (Injection)) - Side Effects, Interactions, Uses Its responsible for carrying oxygen throughout your body. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. *Patients are calculated based on an estimated annual cumulative dose. Properly discard this product when it is expired or no longer needed. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. You will be watched closely by your doctor for 30 minutes after each dose. Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. It is given into a vein for a period of time. Here are answers to some frequently asked questions about Injectafer. Potentialside effectsthat are usually mild may include, but are not limitedto: Theseside effectsmay not impact life too much and may only be temporary. A variety of tests can diagnose iron deficiency anemia. Have blood work checked as you have been told by the doctor. So we cant say for sure whether the drug is safe to use while youre pregnant. You will need to talk about the benefits and risks to you and the baby. What is the latest research on the form of cancer Jimmy Carter has? chills difficulty with moving ear congestion or pain flushed, dry skin fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes However, some people can experienceside effectsfor much longer - days, months, or indefinitely. These drugs have been compared in a clinical trial of adults with both IDA and CKD who didnt need dialysis. So theres no recommended pediatric dosage for Injectafer. And these two doses need to be separated by at least 7 days. Most people will metabolize medication by half every time it circulates the body. A delayed reaction can occur in two different ways: It can happen hours or days after you receive a drug, or it can happen after a second (or later) dose of a drug. Throw away unused or expired drugs. fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing Do not flush down a toilet or pour down a drain unless you are told to do so. Iron is an essential nutrient needed to maintain energy levels and keep you healthy. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. Ask your doctor or healthcare provider if Venofer is the right choice for you. In one study, treatment with Injectafer was compared with that of iron thats taken by mouth. Injectafer isnt a medication that youll take regularly on a schedule. 5 0 obj Hemoglobin is a protein thats found in your RBCs. (A medication class is a group of medications that work in a similar way.). If you have questions about side effects, call your doctor. Below are examples of these side effects. I actually was constipated after my 3rd but didn't think anything of it. However, since peoples bodies react so differently to drugs, they often have to change their stance on certain drugs. If youre taking iron pills, be sure to tell your doctor before starting Injectafer. Possibleside effectsareweight gainand suicidal thoughts. Do not share your drugs with others and do not take anyone else's drugs. MNT is the registered trade mark of Healthline Media. Check with your pharmacist. Vomiting. You may also report side effects at https://www.fda.gov/medwatch. For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. Tell your doctor if you are pregnant or plan to become pregnant. Or your doctor may recommend that you change your eating habits to include more iron in your diet. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. Call your doctor right away if youre having a severe allergic reaction to Injectafer, even if youve had doses of the drug in the past without any problems. The Role of Genetics in Multifactorial Disorders, The Power of DNA Testing and Predictive Medicine, A Guide to Genome Explorer (Free Version), Whole Genome Sequencing in As Little As Three Weeks, What Diseases Can Be Detected Through Genetic Testing, Breast Cancer Genetic Testing: Pros and Cons, At Home Genetic Testing for Breast Cancer, DNA Tests for Breast Cancer Genetic Testing, What to Do When Medicines Have Side Effects, Blood Type and COVID: Infection Risk and Severity, Where Can I Get My Blood Type Checked for Free, How to Find Biological Father Through DNA. This information should not be used to decide whether or not to take Venofer or any other medicine. Some drugs may have another patient information leaflet. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This medicine may cause serious types . Severeside effectsmay end up causing a lot of disruption in a persons life. The benefit of treating your condition during pregnancy may outweigh any risks. You may report side effects to FDA at 1-800-FDA-1088. Administer Venofer in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later. Otherwise, call a poison control center right away. Side effects like nausea and low blood pressure are common with most iron infusions. Get emergency medical help if you have signs of an allergic reaction to Venofer: hives, rash, itching; feeling light-headed; difficulty breathing; swelling of your face, lips, tongue, or throat. (IV iron is absorbed by the body more rapidly than oral iron.) This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. Iron Infusion: Benefits, Side Effects, and What to Expect - Healthline With IDA, you have low hemoglobin levels. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. And this would give you a total cumulative Injectafer dose of 1,440 mg. Injectafer should be given in two doses. This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Back pain. Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft). Consult the product instructions and your pharmacist for storage details. We cancelled my 5th because of the reaction. I had my first infusion of 1gm 10 days ago. If you notice other effects not listed above, contact your doctor or pharmacist. A lack of iron can lead to iron deficiency anaemia if left untreated. Following an LSD trip, users may experience a sort of 'comedown.'. Read all information given to you. pain in the arms or legs. With IV infusion, the drug is given as a slow drip into your vein over a period of time. This allows them to manage any side effects that you may have following your dose. The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. For more information about Injectafers approved uses, see the section Injectafer uses below. This website is intended for use by US patients. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. Wellbutrin: Side effects and how to manage them - Medical News Today The researchers looked to see how well each drug worked to increase peoples hemoglobin level. If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. Its FDA-approved to treat iron deficiency anemia (IDA) in adults. 2. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. Iron infusions are given directly into a vein. For additional information, contact your healthcare provider. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. Side Effects of Intravenous Iron | livestrong (For more information on Venofer, see the Injectafer vs. Venofer section above). Venofer (iron sucrose): Basics, Side Effects & Reviews - GoodRx After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. Brand-name medications usually cost more than generics. cough. Do not start, stop, or change the dosage of any medicines without your doctor's approval. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Selected from data included with permission and copyrighted by First Databank, Inc. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. For example: Say you weigh 105 pounds (about 48 kilograms). reactions at the site of the injection. Symptoms of overdosage include drowsiness, mental confusion, dizziness, diarrhea and vomiting etc. Together, you and your doctor can discuss the benefits and risks of treatment options for anemia. weakness. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre taking Injectafer. This is not a list of all drugs or health problems that interact with this medicine. Yes, in some cases it may. Keep out of reach of children. Theyll recommend how to manage your condition. What are the side effects of Venofer? Then your body uses that iron to make hemoglobin and RBCs. How is Venofer (iron sucrose) given? Copyright 1996-2023 Cerner Multum, Inc. However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. stream All patients receiving Venofer require periodic blood tests to monitor the amount of iron in the blood. This treatment course is split into two doses of the drug, which are given at least 7 days apart. Notify your healthcare provider if you are pregnant, or planning to get pregnant or breastfeeding. Injectafer can cause low blood levels of phosphorus, which is a condition called hypophosphatemia. Also tell them about any vitamins, herbs, and supplements you use. With anemia, you have a low level of red blood cells (RBCs) in your body. People with IDA have low blood levels of hemoglobin. Injectafer infusions are given over a period of at least 15 minutes. It may also cause nervousness, restlessness, and difficulty sleeping in some people. Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. Its caused by your body not having enough iron, which is needed to make hemoglobin. If you are breastfeeding, tell your doctor if you notice diarrhea or constipation in the nursing baby. Daiichi Sankyo, Inc., the manufacturer of Injectafer, offers a program called injectconnect, which may help lower the cost of the drug. 1 0 obj The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. Iron sucrose can make it harder for your body to absorb iron medications you take by mouth. The potential side effects of Daxxify are nearly identical to that of Botox bruising, headaches, and droopy eyelids with one big difference: They could last longer. On day three I had a headache and felt heavy/exhausted, which lasted a few days. Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. If either is present, do not use the liquid. But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. If your symptoms or health problems do not get better or if they become worse, call your doctor. Venofer may reduce the absorption of iron preparations taken by mouth. After receiving IV iron therapy, you will be monitored for 30 minutes to make sure you do not have an allergic reaction or a drop in blood pressure. All rights reserved. In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. The dosing for iron replacement treatment in pediatric patients less than 2 years old with Peritoneal or Hemodialysis-Dependent CKD or Non-Dialysis-Dependent CKD have not been established. Back pain. Your doctor will be able to see how Venofer is working by reviewing your blood tests. 2005 - 2023 WebMD LLC. Cardiovascular health: Insomnia linked to greater risk of heart attack. While the side effects that occur during treatment with these drugs are increasingly well-cataloged, the long-term side effects that may result from receiving these drugs are only beginning to be studied. Feeling awful 10 days after Iron Infusion. Is it normal? To help make sure that you dont miss appointments for your Injectafer doses, try setting an appointment reminder on your phone. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. There are different types of anemia, but IDA is the most common type. For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. Call your doctor right away if you have serious side effects. Other drugs may interact with iron sucrose, including prescription and over-the-counter medicines, vitamins, and herbal products. Together, they can recommend ways to help you manage a body weight thats healthy for you. 1xo`[kg'#KS#.#`uv:PM1+Ob`>y/8:6Ghl:y9B+-,9m[ administered at your doctors office or an infusion center. Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. Source: Wolters Kluwer Health. To make sure Venofer injection is safe for you, tell your doctor if you have: hemochromatosis or iron overload (the buildup of excess iron). In this study, researchers compared Feraheme treatment with that of ferric carboxymaltose (the active drug in Injectafer). No, Injectafer itself wont make you gain weight. (And Injectafer is used to treat IDA.) People who are ongoingcancer treatmentwithradiation therapyor takingchemotherapy drugsmay be more susceptible toside effects. (A class of medications describes a group of drugs that work in the same way.). The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.